CalcuSyn v2 劑量效應分析軟體
- CalcuSyn v2 劑量效應分析軟體
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類別生化統計分析軟體
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介紹Calcusyn是一個劑量效應分析器節目單及多種藥物。它使用位數效應法，以量化的影響，藥物組合，以確定他們是否給予更大的影響，共同表示，預計從一個簡單的總結對他們個人的影響。數據錄入，存儲與其他軟體如試算表和文字處理器是直截了當。數據可被加工個別藥品和恆比和非恆定比例組合多達6種化學物質。程式自動圖表數據並製作報告簡要統計所有藥品和詳細的分析藥物相互作用包括組合指數和能譜分析。
CalcuSyn v2 Dose Effect Analysis Software
CalcuSyn Version 2.0 is the definitive analyzer of combined drug effects, able automatically to quantify phenomena such as synergism and inhibition. Mixed drug treatment is becoming common in the treatment of cancer, AIDS etc, and CalcuSyn is the most widely used software for establishing efficacy in this field. It performs multiple drug dose-effect calculations using the Median Effect methods described by T-C Chou and P. Talalay (Trends Pharmacol. Sci. 4, 450-454).
CalcuSyn can easily be integrated with other software. Data can be entered via the keyboard or file import either into the grid or directly into the analysis engine. When the grid is used, data can be processed through wizards which make the software easily accessible to new users.
Data can be processed both for individual drugs and for constant-ratio or non-constant-ratio combinations of drugs. CalcuSyn automatically graphs the data and produces reports giving summary statistics on all drugs plus detailed analysis of drug interactions including the Combination Index and EDx (for any value of x). Estimates of accuracy of EDx and CI can be calculated with Monte Carlo simulations or by a highly accurate algebraic estimation algorithm. The plots drawn by CalcuSyn include dose-effect, median-effect, isobolograms and CI-effect. All data and results are easily accessible by mouse-click on the contents tree.
CalcuSyn Version 2.0 has Undo and Redo tools. There are flexible arrangements for printing of results and graphs and their export to spreadsheets, wordprocessors, graphics packages etc. A comprehensive manual is supplied as .pdf with the software and there is a detailed Help file. These give a thorough account of the theoretical basis of the analysis methods including the statistical treatment of results. Already used in hundreds of academic labs and pharmaceutical companies, CalcuSyn is indispensable for the study of drug mixtures.
系統需求
Windows Vista, 7, 8 and 10 (32 and 64 bit)
CalcuSyn v2 劑量效應分析軟體
CalcuSyn 2.0 版是綜合藥物效應的權威分析儀，能夠自動量化協同作用和抑制等現象。混合藥物治療在癌症、艾滋病等的治療中越來越普遍，CalcuSyn 是該領域使用最廣泛的建立療效的軟件。它使用 TC Chou 和 P. Talalay (Trends Pharmacol. Sci. 4, 450-454) 描述的中值效應方法執行多種藥物劑量效應計算。
CalcuSyn 可以很容易地與其他軟件集成。數據可以通過鍵盤輸入或文件導入到網格或直接導入分析引擎。當使用網格時，可以通過嚮導處理數據，這使得新用戶可以輕鬆訪問該軟件。
可以處理單個藥物和恆定比例或非恆定比例藥物組合的數據。CalcuSyn 自動繪製數據並生成報告，提供所有藥物的匯總統計數據以及藥物相互作用的詳細分析，包括組合指數和 EDx（對於任何 x 值）。EDx 和 CI 的準確度估計值可以使用蒙特卡羅模擬或高度準確的代數估計算法進行計算。CalcuSyn 繪製的圖包括劑量效應、中值效應、等效線圖和 CI 效應。
CalcuSyn 2.0 版具有撤消和重做工具。結果和圖形的打印以及它們導出到電子表格、文字處理器、圖形包等方面有靈活的安排。軟件隨附了一份 .pdf 格式的綜合手冊，並有詳細的幫助文件。這些給出了分析方法的理論基礎，包括結果的統計處理。CalcuSyn 已經在數百個學術實驗室和製藥公司中使用，對於藥物混合物的研究是必不可少的。
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